Protein and peptide folding, misfolding, and non-folding

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Jaroslav Šesták, Peter Šimon

<p><i>Thermal Analysis of Micro-, Nano- and Non-Crystalline Materials: Transformation, Crystallization, Kinetics and Thermodynamics</i> complements and adds to volume 8 <i>Glassy, Amorphous and Nano-Crystalline Materials</i> by providing a coherent and authoritative overview of cutting-edge themes in the field of crystalline materials. In particular, the book focuses on reaction thermodynamics and kinetics applied to solid-state chemistry and thermal physics of various states of materials.</p><p> </p><p>In this volume the fundamental and historical aspects of phenomenological kinetics and the equilibrium background of processes are detailed. Crystal defects, non-stoichiometry and nano-crystallinity, reduced glass-transition temperatures and glass-forming coefficients are covered.^ The determination of the glass transition by DSC, the role of heat transfer and phase transition in DTA experiments, and the explanation of DTA/DSC methods used for the estimation of crystal nucleation are reviewed. Structural relaxation and viscosity behaviour in glass and associated relaxation kinetics are also examined, together with the influence of preliminary nucleation and coupled phenomenological kinetics nucleation on both the strongly curved surfaces and nano-particles. The book investigates crystallization of glassy and amorphous materials including oxides, chalcogenides and metals, non-parametric and fractal description of kinetics, disorder and dimensionality in nano-crystalline diamond.^ Moreover, it analyzes thermal analysis of waste glass batches, amorphous inorganic polysialates and bioactivity of hydroxyl groups as well as reaction kinetics and unconventional glass formability of oxide superconductors.</p><p> </p><p>Written by an international array of distinguished academics, <i>Thermal Analysis of Micro-, Nano- and Non-Crystalline Materials: Transformation, Crystallization, Kinetics and Thermodynamics</i> is a valuable resource to advanced undergraduates, postgraduates, and researches working in the fields of applied material thermodynamics, thermal analysis, thermophysical measurements and calorimetry.</p><p></p>

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Fuad

The latest edition of this highly acclaimed textbook, provides a comprehensive and up-to-date overview of the science and medical applications of biopharmaceutical products. Biopharmaceuticals refers to pharmaceutical substances derived from biological sources, and increasingly, it is synonymous with 'newer' pharmaceutical substances derived from genetic engineering or hybridoma technology. This superbly written review of the important areas of investigation in the field, covers drug production, plus the biochemical and molecular mechanisms of action together with the biotechnology of major biopharmaceutical types on the market or currently under development. There is also additional material reflecting both the technical advances in the area and detailed information on key topics such as the influence of genomics on drug discovery.

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Michael Ziese, Martin J. Thornton, (eds

For 50 years conventional electronics has ignored the electron spin. The manipulation and utilisation of the electron spin heralds an exciting and rapidly changing era in electronics, combining the disciplines of magnetism and traditional electronics. The first generation of "spintronic" devices (such as read heads based on giant magnetoresistance or non-volatile magnetic random access memories) have already gained dominant positions in the market place. This volume, the first of its kind on spin electronics, describes all the essential topics for new researchers entering the field. It covers magnetism and semiconductor basics, micromagnetism, experimental techniques, material science, device fabrication and new developments in spin-dependent processes. At the end of most chapters are a number of exercises and worked problems to aid the reader in understanding this fascinating new field.

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Günter Kirschling

It is in general not possible to produce technical products having precisely predefined measures. Systematic and random deviations from nominal size cannot be avoided, and it is therefore necessary to define measurement tolerances. This book offers a comprehensive presentation of tolerance problems and their solution by statistical methods. All calculated solutions are presented in clear figure or graphical form. It is particularly appropriate for those working in the field of development and construction or in production and quality control, especially in mechanical engineering and related fields.