In this book the authors introduce health research to junior doctors, nurses, therapists, health educators, and allied health professionals with little or no research experience, leading them through the process of study design, data collection and analysis, writing up results, and submission for publication, and covering both quantitative and qualitative projects.
Setting / LocationGlobal
Story EraModern Era
Protagonist / CoreGetting started in health research Lead Character
The current volume provides detailed experimental protocols used to study plasma membrane ion channels as pharmacological targets. Coverage includes molecular and biochemical characterization of ion channels; fuctional analysis of ion channels after reconstitution, expression, or in cells; and specific methods and tools. This wealth of information will benefit academic and industrial researchers and graduate students in pharmacology, biochemistry, physiology, and biophysics.
This book describes our current understanding of the transport of ions, amino acids, nucleosides, sugars, water and gases across the red blood cell membrane. It also outlines the necessary theoretical background to understand the dynamics of membrane constituents together with the mechanisms of transport pathways (pumps, channels, carriers/cotransporters, residual passive permeability). Separate chapters describe our present ideas about membrane and metabolic disorders as well as red blood cell diseases like malaria, sickle cell disease, and hypertension. The latest findings are explained on the basis of a historical review and well-established principles. The book and its chapters are thus structured in a manner that makes the material accessible to beginners in the field of red blood cell physiology and biophysics. Active researchers will also benefit from this carefully organized compilation.
Never before have the four great works of Charles Darwin--Voyage of the H.M.S. Beagle (1845), The Origin of Species (1859), The Descent of Man (1871), and The Expression of Emotions in Man and Animals (1872)--been collected under one cover. Undertaking this challenging endeavor 123 years after Darwin's death, two-time Pulitzer Prize winner Edward O. Wilson has written an introductory essay for the occasion, while providing new, insightful introductions to each of the four volumes and an afterword that examines the fate of evolutionary theory in an era of religious resistance. In addition, Wilson has crafted a creative new index to accompany these four texts, which links the nineteenth-century, Darwinian evolutionary concepts to contemporary biological thought. Includes restored versions of the original illustrations.--From amazon.com.
Essential in biological functions like cell signaling and, when disturbed, a likely cause of disease, lipids have proven to be a vital force in cell biology. In Lipidomics: Methods and Protocols, an international panel of experts present a wide variety of reviewed as well as unpublished data on isolation techniques, structural analysis, lipid rafts, lipid trafficking and profiling, biomarkers, lipid peroxidation, biostatistics applied to lipids, software tools, and bioinformatics. These studies range from simple systems, such as in yeast, to complex biological models. Samples used in these studies include: mitochondria, microsomes, endosomal membranes, RBS and plasma membranes, vesicles, caveolae, liposomes, macrophages, meibum, brain, microglia, retina, adipose tissue, keratinocytes, pulmonary surfactant, and hepatic cultures. Volume 2 focuses on oxidized lipids, trafficking and profiling, software, bioinformatics, and biostatistics. Written in the highly successful Methods in Molecular Biology"!series format, the chapters include useful introductions to their respective topics, lists of the necessary equipment and materials, step-by-step, readily reproducible laboratory protocols, and authoritative notes on troubleshooting and avoiding common pitfalls. Comprehensive and cutting-edge, Lipidomics: Methods and Protocols will support researchers who wish to increase their utilization of lipidomics, which will certainly lead to more powerful technology, improved diagnostic-prognostic capabilities, and the identification of new valuable products
Getting started in health research by David Bowers, Allan House, David Owens | Literally Just Books
